Thyroid Genetics Test
Discovering Genetic Changes in your Thyroid
There are around 600,000 people in the United States annually that undergo a fine needle aspiration (FNA) biopsy to examine thyroid nodules. During these biopsies, cells are extracted and tested to determine cellular condition (whether they are benign or cancerous) using microscopy/cytology-based methods.
Although accurate, 20%-25% of FNA biopsies are returned with an indeterminate result. Most patients undergo diagnostic surgery, with approximately 60% being overtreated or undertreated. Because of this, microscopical observations of cells from nodules and surgical removal are not the most optimal treatment options for patients.
Today, management of thyroid nodules has expanded to molecular genetic testing, using next generation sequencing (NGS) technology. Highly-sensitive NGS technology determines genetic changes in thyroid nodules, resulting in informative risk assessment and avoidance of unnecessary surgeries.
Our Thyroid Genetics Test examines genetic changes that are relevant for hypothyroidism, thyroid hormone resistance, and thyroid risk panel. This NGS panel consists of 45 genes. These are listed in the table along with the disease-related conditions.
Genes List
- ATP1A2 NRAS
- CACNA1A PAX8
- CST1 PIK3CA
- CST3 PLCG2
- CSTB PLN
- CTNNB1 PRKCG
- DUOX1 SECISBP2
- DUOX2 SLC16A2
- ESR1 SLC26A4
- FOXE1 SLC40A1
- G6PD SLC5A5
- GLIS3 TBL1X
- GNAQ TFR2
- HAMP TG
- HFE TGFBI
- HRAS THRA
- IGSF1 THRB
- IRAK1 TP53
- IRS4 TPO
- IYD TRH
- KRAS TSHB
- MECP2 TSHR
- NKX2-1
Important Questions
Frequently Asked Questions
Have a question? You might find the answer below in our FAQs!
What is your turnaround time for testing?
We offer same day turnaround time for PCR tests. Toxicology tests will be resulted in 24-36 hours, depending upon targets requested.
Where are you located and how can I sign-up for testing?
We have multiple testing locations across the country. You can book here on our website by selecting your desired testing location.
Do you take insurance?
Most insurances are accepted, but must have doctor’s orders to use insurance. Cash pay rates are available, please contact us for a quote.
How do I receive my results?
Secure results are sent by email or through your provider portal, and can also be shared directly with your referring physician.
